Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells
نویسندگان
چکیده
منابع مشابه
Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells.
Genomic reprogramming of primordial germ cells (PGCs), which includes genome-wide demethylation, prevents aberrant epigenetic modifications from being transmitted to subsequent generations. This process also ensures that homologous chromosomes first acquire an identical epigenetic status before an appropriate switch in the imprintable loci in the female and male germ lines. Embryonic germ (EG) ...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1997
ISSN: 1460-2075
DOI: 10.1093/emboj/16.21.6510